The cancers that show high in eosinophils and are associated with eosinophilia are blood cancers and solid tumor cancers.
Solid tumor cancers that are associated with eosinophilia are gastrointestinal cancers like colorectal cancers and gastric cancers, reproductive cancers like breast cancer, prostate cancer, ovarian cancer, cervical cancer and even renal cell carcinoma and lung cancer.
Blood and lymph node cancers that are associated with eosinophilia are leukemias like chronic and acute eosinophilic leukemias and other myeloid neoplasms and certain acute lymphoblastic leukemias.
And lymphomas like Hodgkin Lymphoma and some Non Hodgkin Lymphomas, especially T-cell lymphomas.
Although eosinophils are crucial in the body for fighting off certain parasites and also for controlling infections, excessively high levels of eosinophils also known as eosinophilia can result in them infiltrating and damaging of health tissue, which leads to severe localized or even systemic complications.
When the eosinophils migrate out of your bloodstream and into your tissues, they will release toxic proteins, which cause chronic inflammation and organ damage.
The specific health issues that eosinophilia causes, depends on where the cells actually accumulate.
Heart damage or cardiovascular damage is the most dangerous complication with eosinophilia.
High eosinophil levels can cause inflammation of your heart muscle, which is also known as myocarditis, heart failure and even blood clots, which also increase your risk of heart attacks or stroke.
lung and respiratory issues can also occur with eosinophilia as infiltration of the airways causes severe inflammation, mucus hypersecretion and even airway constriction, which significantly worsens conditions such as asthma.
Gastrointestinal complications can also occur with eosinophilia, as excess eosinophils in your digestive tract can trigger Eosinophilic Gastrointestinal Diseases, which causes severe acid reflux, swallowing difficulties, stomach pain and even tissue damage.
Infiltration can also cause skin problems, like chronic rashes, severe itching or pruritus, hives or angioedema "swelling.
And in severe cases of eosinophilia, like Hyper eosinophilic Syndrome, eosinophils can also affect your brain and your nerves, potentially resulting in confusion, nerve damage or behavioral changes.
And chronic or extreme levels of eosinophils may also be a warning sign for underlying bone marrow disorders like chronic Eosinophilic Leukemia and myeloproliferative diseases.