The side effects of SKYTROFA include viral infections, fever (pyrexia), cough, nausea and vomiting, diarrhea, stomach (abdominal) area pain, bleeding (hemorrhage), joint pain (arthralgia), and arthritis, as well as mild injection-site reactions in children.
And in adults the side effects of SKYTROFA include swelling due to fluid build-up (edema) and low thyroid hormone levels (hypothyroidism), along with joint pain, numbness, and dizziness.
Serious side effects of SKYTROFA include fluid retention, high blood sugar and diabetes, decreased hormone levels, intracranial hypertension, bone and spine issues in children, pancreatitis, tumor growth risk, severe allergic reactions and infection site tissue changes.
Fluid retention involves excess fluid in the body causing swelling in the hands and feet, joint or muscle pain, or carpal tunnel symptoms (burning or tingling).
High blood sugar and diabetes involve new or worsening high blood sugar levels or diabetes.
Decreased hormone levels involve drops in cortisol, (which causes extreme fatigue, dizziness, weakness, or skin darkening) or even drops in thyroid hormone.
Intracranial hypertension involves increased pressure inside your brain, leading to headaches, vision changes, or nausea.
Bone and spine issues in children involve slipped capital femoral epiphysis (hip or knee pain, or a limp that can lead to bone tissue damage/osteonecrosis) and the progression of scoliosis (curvening of the spine).
Pancreatitis involves severe and constant stomach pain, which can also be a sign of inflammation of the pancreas.
Tumor growth risk, involves increased risk of growth of an existing tumor/cancer or recurrence in pediatric brain/head radiation survivors.
Severe allergic reactions involve face, mouth, tongue, or throat swelling or difficulty breathing.
And injection site tissue changes include loss of fat or tissue weakness at the injection site which is minimized by rotating the injection spots.