What happens to the body when you have too much pepsin, is it result in and causes severe tissue damage, gastrointestinal distress as well as inflammation as pepsin is a powerful stomach enzyme that breaks down proteins.
Although often confined to your stomach, excessive or too much pepsin can sometimes backflow and adhere to sensitive respiratory and throat tissues.
Complications that can occur from too much pepsin are gastritis and ulcers, pan and nausea and even reflex and throat damage.
When the pepsin escapes your stomach through reflux, the pepsin can attach to the delicate tissues of your airways and throat, which is known as Laryngopharyngeal Reflux or silent reflux.
Even if the stomach acid is neutralized, pepsin can still remain in your throat for hours and can reactivate whenever you consume acidic foods or beverages, and once reactivated, the pepsin breaks down the proteins in your throat and vocal cords, triggering of inflammation.
Common symptoms of reflux and throat damage are chronic sore throat, hoarseness, a persistent cough, postnasal drip and difficulty swallowing.
The erosion from the excess pepsin can also lead to indigestion, a burning stomach sensation, nausea, bloating and mild pain.
And an over abundance of active pepsin in your stomach can erode your protective mucosal lining.
If you have too little pepsin, what happens is your body struggles to break down the dietary proteins.
The inefficiency of too little pepsin, triggers a cascade of digestive issues, nutritional deficits and physical discomfort.
When you have too little pepsin, it leads to poor digestion, increased infection risk and nutritional deficiencies.
With too little pepsin, large protein molecules are not cleaved into absorbable peptides.
This also causes food to linger in your stomach, fermenting and producing gas.
And pepsin and stomach acid are also required to extract and absorb critical nutrients like iron, vitamin B12, calcium and magnesium.
Stomach acid also acts as the primary barrier against pathogens.
And low levels of pepsin and stomach acid makes your GI tract more vulnerable to bacterial overgrowth, like SIBO and infections.
Common symptoms of too little pepsin include.
Fatigue, brain fog and muscle cramps.
Weak, brittle nails or hair that thins over time.
Having undigested food particles in your poop.
Experiencing feeling of extreme fullness just shortly after starting a meal.
And bloating, gas and belching, especially after eating meals heavy in protein.
If your stomach stopped producing pepsin, your body would struggle to digest proteins.
This would lead to severe gastrointestinal distress, bloating, and potential long-term malnutrition, although your small intestine would attempt to compensate using pancreatic enzymes to break the proteins down.
Pepsin is the enzyme responsible for initiating the digestion of proteins into smaller peptide chains.
Without the pepsin, intact proteins can move into the large intestine where they ferment, causing significant gas, bloating, and discomfort.
Because protein isn't efficiently pre-digested in the stomach, your body may also fail to absorb essential amino acids over time, leading to potential muscle loss and malnutrition.
Pepsin also functions in a highly acidic environment driven by hydrochloric acid (HCl).
Together, this acid-enzyme combination plays a vital role in destroying harmful bacteria and pathogens ingested with your food.
Without pepsin and optimal acidity, your risk for gastrointestinal infections spikes.