Does phenylephrine affect the brain?

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asked Dec 1, 2022 in Other- Health by CarkHubbard (8,000 points)
Does phenylephrine affect the brain?

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answered Dec 5, 2022 by Shawn (99,990 points)
Phenylephrine does affect the brain and can affect the frontal lobe cerebral tissue oxygenation (rSO2) with a decrease after administration of phenylephrine.

Phenylephrine is not like codeine as Codeine is a narcotic cough suppressant which affects the signals in your brain which trigger the cough reflex while Phenylephrine is a decongestant which shrinks blood vessels in your nasal passages.

Dilated blood vessels can lead to stuffy nose and nasal congestion.

The amount of phenylephrine that is toxic is dosages of 5–6 mg/kg, and death can occur at 10–12 mg/kg dosages of phenylephrine.

Phenylephrine is toxic when you overdose on it although when taken in proper dosages the phenylephrine is not toxic and safe to use.

The type of drug that phenylephrine is, is a nasal decongestant which works by reducing swelling of your blood vessels in your nasal passages.

Phenylephrine was used and is used during surgery to treat low blood pressure that can occur during surgery and is given through injection.

Phenylephrine is not addictive although some people have a rebound on phenylephrine which is mistaken for addiction.

The typical phenylephrine dose is 10 mg by mouth every 4 hours.

Don't take more than 60 mg of phenylephrine in a 24-hour period.

Once you stop taking phenylephrine it takes the phenylephrine around 2 to 3 hours to leave your system although in some cases it may take around 10 hours for the phenylephrine to leave your system.

Phenylephrine does sometimes raise blood pressure as the medication phenylephrine can affect your blood vessels which can  increase blood pressure.

Phenylephrine is a combination of an antihistamine and a decongestant.

The nervous system that phenylephrine affects are the parasympathetic and the sympathetic nervous system.

You can take an antihistamine with phenylephrine as no interactions have been found between them.

Phenylephrine does sometimes make your heart race and can raise your blood pressure and may cause heart palpitations as well.

Phenylephrine does loosen mucus and makes it easier to cough the mucus up.

And Phenylephrine is a decongestant which clears up your sinuses and relieves sinus pressure as well.

The OTC medications that have phenylephrine are Vicks Sinex, Tur- Bi Cal, Rhinall, Pretz-D, Nostril and Neo Synephrine.

The reason phenylephrine keeps you awake is because phenylephrine stimulates your alpha-adrenergic receptors which may make it responsible for central nervous system stimulant effects such as restlessness, anxiety, and insomnia.

People who should not use phenylephrine are people who are taking a monoamine oxidase (MAO) inhibitor, such as isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate), and if you have stopped taking one of these medications within the past 2 weeks.

Phenylephrines common names are NeoSynephrine Nasal and Neo-Synephrine Cold & Sinus Mild Strength Spray.

Phenylephrine is the same as Sudafed PE as the active ingredient in Sudafed is pseudoephedrine, while the active ingredient in Sudafed PE is phenylephrine.

The medication phenylephrine is an opioid as it has an opioid in it.

Misuse or abuse of phenylephrine, dexchlorpheniramine, and codeine can lead to overdose and death.

The medication phenylephrine is not a Benadryl.

Benadryl is Diphenhydramine which clears sinuses while Phenylephrine is a Sudafed  Pe which is a medication used for relieving stuffy nose.

The medication phenylephrine is used for temporary relief of congestion or stuffiness in the nose that is caused by hay fever or other allergies, colds, or sinus trouble.

The side effects of phenylephrine are mild upset stomach, trouble sleeping, dizziness, lightheadedness, headache, nervousness, shaking, or fast heartbeat.

If you experience these side effects when taking phenylephrine and they last too long or get worse you should tell your doctor.

Phenylephrine is not a sedative although some people may experience drowsiness when taking it.

Although most people who take phenylephrine do not experience sleepiness or a sedative effect.

Phenylephrine is in a class of medications called nasal decongestants.

It works by reducing swelling of the blood vessels in the nasal passages.

Phenylephrine does stimulate alpha-adrenergic receptors which may make it responsible for central nervous system stimulant effects such as restlessness, anxiety, and insomnia.

It is thought that it may not cause the effects to the extent that pseudoephedrine does, however.

Two commonly-used decongestants are pseudoephedrine (Sudafed) and phenylephrine (Sudafed PE).

These medications work great to clear nasal passages and help us breathe better.

But to our bodies, they look very similar to the stimulants discussed earlier and can have the same side effects, including anxiety.

Blood pressure increased at 5 and 10 minutes after application of phenylephrine 10% (mean difference 15 mmHg; 95% CI = 12, 19) but fell to baseline after 20–30 minutes.

The heart rate increased by 5/minute (95% CI = 1, 8) at 20–30 minutes and returned to baseline after 60 minutes.

Phenylephrine and norepinephrine increase dopamine transporter ligand binding in striatum.

Mol Imaging Biol.

Phenylephrine is used for the temporary relief of congestion or stuffiness in the nose caused by hay fever or other allergies, colds, or sinus trouble.

It may also be used in ear infections to relieve congestion.

This medicine may also be used for other conditions as determined by your doctor.

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