If you have a tire bubble you can drive for around 100 miles or sometimes longer before it pops.
However the tire bubble may pop sooner depending on how bad it is.
If you're just driving in town then it may be okay to drive with a bubble in your tires sidewall but if you're planning on driving on the highway then you should not drive on the tire bubble as it could blowout.
Tire delamination is when the tires tread separates from the tires casing.
When tire delamination occurs the tire is basically just tearing itself apart with the outer and inner components separating.
The bond between the casing and the tread can be compromised and lead to tread separation for a variety of reasons, including manufacturer's defects, tire abuse, incorrect flat repair, underinflation and excessive tire wear.
Radial tires are constructed by laying steel belts between layers of rubber and composite.
Each layer is a "plie" and these plies are laminated to one another when the tire is created.
If the steel belts become warm enough (typically because of under-inflation), they can separate from the rubbers plies, aka "delaminate."
If you notice tire delamination you need to change the tire and have a new tire put on the rim.
Driving with a tire delaminating means that the tire could blow out soon and at high speeds that can be really dangerous and even lead to a fatal crash.
Always replace tires when needed as they are not something you want to cheap out on.
Some peoples tires age and crack and delaminate before the tread actually wears down and regardless of tread wear the tires should be replaced every 8 to 10 years.