Is denosumab chemotherapy?

0 votes
asked Dec 23, 2020 in Diseases Conditions by Paletta (1,160 points)
Is denosumab chemotherapy?

1 Answer

0 votes
answered Nov 25, 2021 by lulumeon (40,850 points)
No the denosumab drug is not a chemotherapy drug.

Denosumab which is also known as Xgeva is not a chemotherapy drug.

Instead it is a targeted treatment, called a monoclonal antibody and is classified as a bone-modifying agent.

Although it is not a chemotherapy drug it is often given with chemotherapy medicines.

Denosumab injection (Xgeva) is used Denosumab injection is in a class of medications called RANK ligand inhibitors.

It works to prevent bone loss by blocking a certain receptor in the body to decrease bone breakdown.

It works to treat GCTB by blocking a certain receptor in the tumor cells which slows the tumor growth.

Denosumab (trade names Prolia and Xgeva) is a human monoclonal antibody for the treatment of osteoporosis, treatment-induced bone loss, metastases to bone, and giant cell tumor of bone.

Denosumab is contraindicated in people with low blood calcium levels.

Denosumab injection (Xgeva) is used Denosumab injection is in a class of medications called RANK ligand inhibitors.

It works to prevent bone loss by blocking a certain receptor in the body to decrease bone breakdown.

It works to treat GCTB by blocking a certain receptor in the tumor cells which slows the tumor growth.

In clinical trials of women with osteoporosis and low bone mineral density, denosumab has been well tolerated, with overall rates of adverse events and serious adverse events in women treated with denosumab similar to those receiving placebo.

People with rare hereditary problems of fructose intolerance should not use denosumab.

This medicinal product contains less than 1 mmol sodium (23 mg) per 60 mg i.e. essentially 'sodium-free'.

52,224 questions

57,431 answers

614 comments

2,947,716 users

...