In my experience with the kids I babysit Pampers seem to work better.
I use both Pampers and Huggies for different kids that I babysit depending on which brand the parent buys for the kid.
Pampers leak less and hold up better than Huggies. Plus they have the new Sag to Swag Extra Absorb Channels in there cruisers diaper line which helps distribute wetness evenly and prevent a sagging diaper.