The temperature at which Prions are destroyed is 900 F and above.
To kill off and destroy Prions you need to heat the Prions up to 900 F and above for at least a few hours to fully destroy the prions.
Prions are unable to survive temperatures of 900 F and the higher the temperature the quicker the Prions are destroyed.
Prions are misfolded proteins that have the ability to transmit their misfolded shape onto normal variants of the same protein.
The Prions characterize several fatal and transmissible neurodegenerative diseases in humans and many other animals.
As long as the Prions are heated up enough then the Prions will be destroyed.