Yes Kawasaki disease can and does sometimes affect the brain of someone who has it.
The Kawasaki disease makes children ill by triggering inflammation in many different parts of the body and can also cause a type of meningitis (inflammation of membranes covering the brain and spinal cord.)
The Kawasaki disease can also cause inflammation in the skin, eyes, lungs, lymph nodes, joints and mouth.
Kawasaki disease does run in families.
If the parent or parents have had Kawasaki disease as a child then the child of those parents or parent is likely to also get Kawasaki disease.
It doesn't always mean the child of a parent who had Kawasaki disease will get the Kawasaki disease themselves but there is a higher chance of a child becoming infected with the Kawasaki disease if one or both of their parents had the Kawasaki disease as a child.
The Kawasaki disease may also be inherited through other family members as well.
If someone in your family has had Kawasaki disease as a child then the child is twice as likely to get Kawasaki disease than a child who has no Kawasaki disease in the family.