Yes the Clorox Toilet Wand is very safe for septic systems.
The Clorox Toilet Wand has been tested by Clorox to be safe and effective for use in both sewer and septic systems so it will not do any harm to your septic system to use the Clorox Toilet Wand.
After using the Clorox Toilet Wand you should release the disposable cleaning head and dispose of the Clorox Toilet Wand cleaning head into the trash can.
Do not flush the disposable cleaning heads of the Clorox Toilet Wand as it can clog your sewer system or harm your septic system.
But the chemicals used for the toilet wand cleaning heads is safe for use in septic systems and does not require any other cleaning agents to clean the toilet with.