The cost to drive your vehicle 2,000 miles will depend on the cost of gasoline on your route and the miles per gallon your vehicle gets.
If your vehicle gets 25 MPG it would take you $160.00 to $180.00 in gasoline to drive 2,000 miles depending on gasoline prices but I would budget at least $200.00 for gasoline or a bit more just to be safe because gasoline prices can vary from location to location.
If your vehicle uses more gasoline then it could cost you $300.00 to $500.00 in gasoline to drive 2,000 miles.
So you would take your vehicles miles per gallon and multiply it by how many miles you would drive to get the amount of gallons of gasoline your vehicle will use.