Are there medications that affect the circadian clock?

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asked 2 days ago in Other- Health by Musicalthree (900 points)
Are there medications that affect the circadian clock?

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answered 1 day ago by cabbagehead (29,810 points)
There are several medications that affect the circadian clock, which can be either intentionally as a primary treatment mechanisms for sleep disorders or as a side effect of the medications action in the body.

Chronobiotics are medications that are specifically used to treat circadian rhythm sleep and wake disorders by helping to align your body's internal clock with the external environment.

Tasimelteon also known as Hetlioz also affects the circadian clock and is an FDA approved prescription drug that is used specifically for adults with Non 24 hour sleep and wake disorder which is a condition that is common in people that are totally blind where their body clock is out of sync with the normal day and night cycle and for nighttime sleep problems in children that have Smith Magenis Syndrome.

Even Rozerem also known as Ramelteon can affect the circadian clock, Rozerem or Ramelteon is a prescription medication that is used and approved for sleep onset insomnia and it helps promote sleep by acting as a melatonin receptor agonist.

And melatonin supplements which are available over the counter in the United States help you fall asleep and help treat jet lag and certain sleep disorder when they are taken at the proper time.

The part of the brain that controls the circadian clock is the Suprachiasmatic Nucleus (SCN), which is a tiny cluster of nerve cells that are located in your hypothalamus at the base of the brain, which acts as your body's natural master clock that syncs to the light and dark cycle and signals other parts of the body for sleep.

The specialized cells located in your eyes, detect light, especially sunlight and send signals directly to the Suprachiasmatic Nucleus (SCN).

The Suprachiasmatic Nucleus (SCN), then receives these signals and in turn coordinates internal clock cells throughout your body and ensures that they run on a consistent schedule.

And when it's dark, the Suprachiasmatic Nucleus (SCN) signals your pineal gland to release melatonin, which is a hormone that makes you feel sleepy, while it also triggers the release of cortisol in the morning to wake you up.

The circadian cycle clock is the body's natural internal 24 hour master clock that help you sleep and is located in your brain's SCN (Suprachiasmatic Nucleus), and regulates sleep-wake patterns, release of hormones, body temperature as well other functions and it does by responding to light and dark cues.

The circadian cycle clock is a biological rhythm, which is also known as the circadian rhythm, and synchronizes the internal process with external day and night cycle, influencing when you feel sleepy, by melatonin release and alert which is when your cortisol levels rise.

The organ that is responsible for circadian rhythm is the Suprachiasmatic Nucleus (SCN).

The Suprachiasmatic Nucleus (SCN), which is responsible for circadian rhythm is located in the hypothalamus of your brain, which is the master clock which regulates your body's circadian rhythms, and receives light signals from your eyes to synchronize the body's internal clocks, which include controlling of the production and release of melatonin by the pineal gland for sleep.

The way the Suprachiasmatic Nucleus (SCN) works is specialized cells in the retina detect light and then send signals via the retinohypothalamic tract directly to your Suprachiasmatic Nucleus (SCN).

The Suprachiasmatic Nucleus (SCN) also processes these light cues, and acts as the central pacemaker which also coordinates billions of other cellular blocks that are throughout your body.

And based on the light-dark cycle, the Suprachiasmatic Nucleus (SCN) signals your pineal gland to release melatonin, which is a sleep inducing hormone at night and suppress the melatonin during the day.

The Suprachiasmatic Nucleus (SCN) also sends signals to other brain areas and also peripheral issues like your heart, liver and kidneys to keep their clocks also in sync with the master clock and the environment.

The key structures involved in the circadian rhythm are the Suprachiasmatic Nucleus (SCN), which is the brain's main and primary circadian pacemaker.

The hypothalamus, which is your brain's region where the Suprachiasmatic Nucleus (SCN) resides.

The retina, which detects light and is the primary cue.

And the pineal gland that produces melatonin under Suprachiasmatic Nucleus (SCN) control.

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