The safest calcium channel blocker is longer-acting dihydropyridine (DHP) calcium channel blockers like amlodipine.
The longer-acting dihydropyridine (DHP) calcium channel blockers like amlodipine are often preferred for treating hypertension because of their safety profile in hypertension.
Although non-dihydropyridines like diltiazem and verapamil are often preferred for treating specific heart related issues like angina or arrhythmias and may be more appropriate and safer for these conditions.
However non-dihydropyridines like diltiazem and verapamil can cause different side effects such as excessive slowing of the heart rate and constipation.
The non-dihydropyridines like diltiazem and verapamil are drugs that affect both blood vessels and the heart, slowing your heart rate and reducing the force of contractions.
The non-dihydropyridines like diltiazem and verapamil are often used for treating heart conditions like angina and arrhythmias.
Although non-dihydropyridines like diltiazem and verapamil are also more likely to cause constipation and can also slow the heart rate excessively or lower your blood pressure too much.
And non-dihydropyridines like diltiazem and verapamil are not usually recommended in people with heart failure with a reduced ejection fraction.
The longer-acting dihydropyridine (DHP) calcium channel blockers like amlodipine are drugs that are primarily vasodilators and are often used for treating hypertension.
Examples of longer-acting dihydropyridine (DHP) calcium channel blockers are amlodipine, felodipine, nicardipine and nifedipine.
The longer-acting dihydropyridine (DHP) calcium channel blockers are often safer for treating hypertension and amlodipine is frequently prescribed for treating high blood pressure.
Although, while generally safe, some longer-acting dihydropyridine (DHP) calcium channel blockers like amlodipine can cause side effects like acid reflux and in some people nifedipine can worsen chest pain.