Okami in English means "wolf" when referring to the general sense of the word.
Although the word Okami is also a title video game, Okami, which means "great god".
Okami in the video game meaning is a pun on the word for wolf.
The Okami game follows the sun goddess Amaterasau, who takes the form of a white wolf to save the world.
The Okami game is also known for it's unique sumi-e inspired art style, a "Celestial Brush" mechanic for drawing so a story that is based on Japanese folklore.
The word Kami means deity, but it's also a completely different word/character from the above.
So the word Ookami lso be a character for the "great".