What is the best treatment for Lennox-Gastaut syndrome?

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asked 2 days ago in Diseases Conditions by Semisweetme (900 points)
What is the best treatment for Lennox-Gastaut syndrome?

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answered 2 days ago by Tarabaesing (6,370 points)
The best treatment for Lennox-Gastaut syndrome will depend on the specific types of seizures and the persons individual response.

Although the best treatment for Lennox-Gastaut syndrome often includes dietary therapies and medications and in some cases surgery.

Valporate is often the first line treatment for Lennox-Gastaut syndrome and can be used in combination with other medications.

The new treatment for Lennox-Gastaut syndrome are antiepileptic medications including cannabidiol and fenfluramine.

Surgery is also another treatment for Lennox-Gastaut syndrome.

The surgery for Lennox-Gastaut syndrome are vagus nerve stimulation and corpus callosotomy as well as possible resective surgery and sterotactic laser anterior corpus callosotomy.

Corpus Callosotomy is a surgical procedure that involves the disconnecting of the corpus callosum, the structure connecting the two hemispheres and is often used to reduce atonic seizures and reduce seizure reduction in some cases.

Vagus Nerve Stimulation involves the implanting of a device in the chest to stimulate the vagus nerve, which can help reduce the frequency of seizures and also the intensity.

Vagus nerve stimulation is a less invasive surgical procedure when compared to corpus callostomy.

Resective surgery involves the removing of a portion of the brain where the seizures originate from and is most often done in the temporal lobe of the brain and can result in reduction of seizures significantly.

Other treatments for Lennox-Gastaut syndrome are antiepileptic medications including cannabidiol and fenfluramine.

Lennox-Gastaut Syndrome is treated through use of anti seizure medications, dietary therapies, Neuromodulation, supportive care and medications for associated disorders, respite care and in some cases through epilepsy surgery.

Common medications used to treat Lennox-Gastaut syndrome are clobazam, valproate, felbamate, lamotrigine, topiramate, cannabidiol and rufinamide.

Dietary therapies such as through the ketogenic diet is high in fat and low in carbohydrates and can be very effective in reducing the frequency of seizures.

Neuromodulation uses vagus nerve stimulation to reduce seizures.

Supportive care to treat and manage Lennox-Gastaut Syndrome includes occupational therapy, speech therapy, physical therapy as well as individualized education plants to address the challenges that are associated with Lennox-Gastaut Syndrome.

And respite care can provide families with a break and help them cope with the challenges of caring for someone or yourself with Lennox-Gastaut Syndrome.

An estimated 1 to 2 million people in the world have Lennox-Gastaut Syndrome.

Lennox-Gastaut syndrome represents around 1 to 2 percent of all people that have epilepsy and 3 to 4 percent of all children with epilepsy.

It's estimated that at least 48,000 adults and children in the United States has Lennox-Gastaut Syndrome.

You cannot usually grow out of Lennox-Gastaut syndrome as it's a lifelong condition.

The symptoms of Lennox-Gastaut syndrome can change over time, with different types of seizures and the frequency of the seizures can also change in adulthood and childhood but the Lennox-Gastaut syndrome will still persist.

In very rare cases a person may outgrow Lennox-Gastaut syndrome but it's a very rare occurrence and most people with Lennox-Gastaut syndrome have at least some level of permanent cognitive impairment.

The complications of Lennox-Gastaut syndrome include developmental delays, seizures, behavioral problems and increased risk of death.

Other complications of Lennox-Gastaut syndrome include difficulty swallowing and breathing which can lead to aspiration of fluids and food into your lungs, which can result in pneumonia from the seizures.

Status Epilepticus, injuries, traumatic brain injury and even Sudden Unexpected Death in Epilepsy are other complications of Lennox-Gastaut syndrome.

Status Epilepticus is a prolonged seizure event which can be life threatening and is also a significant complication of Lennox-Gastaut syndrome.

Seizures as a result of Lennox-Gastaut syndrome can cause injuries and falls and lead to traumatic brain injures as well as other injuries.

Having seizures with Lennox-Gastaut syndrome can also lead to developmental delays in areas like motor skills, language and cognitive abilities.

And many people with Lennox-Gastaut syndrome also experience behavioral challenges, which include hyperactivity, aggression and difficulty in following of routines.

And the seizures and Lennox-Gastaut syndrome can cause intellectual impairment which can get worse overtime.

Lennox-Gastaut syndrome can also lead to emotional problems such as anxiety and depression and many medications that are used to treat Lennox-Gastaut syndrome can also have side effects including aplastic anemia and liver failure.

Lennox-Gastaut syndrome is progressive as the seizures can be difficult to control and the behavioral and cognitive impairment that is associated with Lennox-Gastaut syndrome often gets worse over time, most particularly with persistent seizures.

Lennox-Gastaut syndrome (LGS) is a severe type of epilepsy syndrome that is characterized by multiple types of seizures which include tonic, atonic, atypical absence, myoclonic and generalized tonic clonic seizures.

These types of seizures in Lennox-Gastaut syndrome are often resistant to multiple medications and the condition can also cause significant developmental and intellectual challenges.

Lennox-Gastaut syndrome is considered the most severe type of epilepsy because it involves several different types of seizures and some of which are more likely to cause injuries.

And seizures in Lennox-Gastaut syndrome can even often lead to brain damage and cause learning difficulties, developmental setbacks and loss of previously learned abilities.

Lennox-Gastaut syndrome seizures are often difficult to control with medications and multiple medications may be required, but complete control of the seizures is rare.

People with Lennox-Gastaut syndrome can live into their 50s and 60s although some are more likely to die prematurely as a result of the underlying brain disorder, seizures and injuries, aspiration, accidents, pneumonia or even Sudden Unexpected Death in Epilepsy.

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