The most expensive antibiotic is cephalosporins although it's not very expensive and can cost $10.00 to $20.00 for 100 tablets or $70.00 to $100.00 per vial.
The most expensive drug is Lenmeldy also known as atidarsagene autotemcel which is the most expensive drug in the USA with a wholesale acquisition cost of $4.25 million dollars for a single treatment is a gene therapy and not an antibiotic and is approved by the FDA for treating certain types of metachromatic leukodystrophy in children and is a one time treatment which uses the child's own blood stem cells.
Functional copies of the ARSA gene are added to the stem cells and the modified stem cells are then infused back into the child.
This is for a single dose of Lenmeldy although other drugs and antibiotics that are taken in more than one dose can be expensive but they don't reach the multi million dollar price tag of Lenmeldy.
The top three antibiotics are Amoxicillin, Amoxicillin clavulanate or Augmentin and Azithromycin.
Amoxicillin is a penicillin type antibiotic which is often the first choice for many common types of infections such as skin infections, pneumonia, ear infections and even urinary tract infections.
Amoxicillin clavulanate or Augementin is a combination antibiotic that combines amoxicillin with clavulanate, which helps to overcome some certain types of bacterial resistance.
Augmentin is frequently used in treating of ear infections, respiratory tract infections and other conditions in which resistance may be a concern.
Azithromycin is a macrolide antibiotic which is effective against a range of bacteria and is often used for skin infections, some sexually transmitted infections and respiratory infections.
The most powerful or potent antibiotics are carbapenems like imipenem and meropenem and are used for more serious infections or when resistance to antibiotics occurs.
Vancomycin is also another powerful antibiotic and is often used as a last resort due to it's effectiveness against multi drug resistant bacteria, although resistance to vancomycin has also emerged in some strains.
A newly discovered antibiotic is Clovibactin, which also shows great promise in combating of multi drug resistant bacteria by targeting of a broad spectrum of pathogens in a unique way.