Do B cells come back after Ocrevus?

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asked Oct 26, 2024 in Other- Health by Hanzlicek (700 points)
Do B cells come back after Ocrevus?

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answered Oct 26, 2024 by Jamie (68,360 points)
B cells do often come back after ocrevus.

3 percent to 5 percent of people with MS experience 1 percent of B cells coming back at 6 months after the last Ocrevus infusion following 3 to 4 cycles of Ocrevus.

50 to 55 percent experience B cells returning at 9 months and 85 percent to 90 percent of people experience B cells coming back at 12 months.

Ocrevus is not a chemo drug but instead Ocrevus is an immunosuppressant drug.

Immunosuppressant drugs like Ocrevus work by lessening the activity of your immune system.

Chemotherapy drugs work by destroying cells that grow much more rapidly than healthy cells like cancer cells.

The drug Ocrevus belongs to a class of drugs called monoclonal antibodies.

Ocrevus works in the body by decreasing the activity of your immune system and stopping it from attacking your body.

Taking Ocrevus may increase your risk for cancer, including breast cancer.

People who took Ocrevus in clinical trials had a higher rate of cancer development than people who took a placebo or a similar drug.

(A placebo is a treatment with no active drug.)

When taking Ocrevus you should avoid being being near people who are sick or have infections while you are using the Ocrevus.

Also when taking Ocrevus you should wash your hands often.

And you should also tell your doctor if you have ever had an infection that would not go away or an infection that kept coming back.

Taking Ocrevus can also increase your risk of infections, including infections of your nose, throat, airways, lungs, and skin.

The drug Ocrevus can also increase your risk of herpes infection.

You should call your doctor right away if you have an infection or any of the following symptoms which include Hepatitis B Virus Reactivation.

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