Quinine cannot be crushed, opened or chewed and the Quinine tablets should be taken whole with a glass of water.
The medications that should never be crushed are coated tablets and the following medications.
Acetaminophen ER (Tylenol 8HR)
Aspirin EC (Ecotrin)
Bisacodyl (Dulcolax)
Alprazolam ER (Xanax XR)
Bupropion ER (Aplenzin, Forfivo XL, Wellbutrin SR/XL)
Oxycodone ER (OxyContin, Xtampza ER)
Morphine sulfate ER (MS Contin)
Amoxicillin / clavulanate ER (Augmentin XR)
ABBATIN.
Diclofenac / Misoprostol.
Rabeprazole.
Cyclobenzaprine.
Aspirin.
Acxion ap.
Akineton delayed
Estradiol/drospirenone.
Angiotrofin delayed.
Farma Leal ASOFLON LP 0.4 mg 30 Caps.
Atemperator.
Hazardous medications.
Modified release medicines.
Not crushing the medicines is of particular importance with hormonal, cytotoxic or steroidal medications.
If the tablet is crushed, the drug may go into the air and the dose inadvertently be received by the administrating nurse or carer.
Crushing extended-release meds can result in administration of a large dose all at once.
Crushing delayed-release meds can alter the mechanism designed to protect the drug from gastric acids or prevent gastric mucosal irritation.
Crushing sublingual or buccal tabs can alter effectiveness.
Medications may be inappropriate to crush if they have enteric or slow-release coatings; are sublingual or buccal formulations; have the potential to irritate the skin or mouth when crushed; have antineoplastic, cytotoxic, or teratogenic properties; or have a potentially unacceptable taste.
Crushing enteric coated tablets may result in the drug being released too early, destroyed by stomach acid, or irritating the stomach lining.
In general, manipulation of enteric coated and extended-release formulations is not, therefore, recommended.