Can Zofran tablets be crushed?

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asked Jul 25, 2024 in Other- Health by Luciream (1,100 points)
Can Zofran tablets be crushed?

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answered Jul 25, 2024 by Jamie (68,360 points)
Zofran tablets cannot be crushed or cut in half as Zofran tablets are oral disintegrating tablets which dissolve in the mouth very quickly.

When taking Zofran tablets simply allow the Zofran tablets to dissolve in your mouth and swallow it with Saliva and you don't need water to take Zofran as drinking water with Zofran can actually increase your chance of getting a headache.

Other medications that should never be crushed are coated tablets and the following medications.

Acetaminophen ER (Tylenol 8HR)
Aspirin EC (Ecotrin)
Bisacodyl (Dulcolax)
Alprazolam ER (Xanax XR)
Bupropion ER (Aplenzin, Forfivo XL, Wellbutrin SR/XL)
Oxycodone ER (OxyContin, Xtampza ER)
Morphine sulfate ER (MS Contin)
Amoxicillin / clavulanate ER (Augmentin XR)
ABBATIN.
Diclofenac / Misoprostol.
Rabeprazole.
Cyclobenzaprine.
Aspirin.
Acxion ap.
Akineton delayed
Estradiol/drospirenone.
Angiotrofin delayed.
Farma Leal ASOFLON LP 0.4 mg 30 Caps.
Atemperator.
Hazardous medications.
Modified release medicines.

Not crushing the medicines is of particular importance with hormonal, cytotoxic or steroidal medications.

If the tablet is crushed, the drug may go into the air and the dose inadvertently be received by the administrating nurse or carer.

Crushing extended-release meds can result in administration of a large dose all at once.

Crushing delayed-release meds can alter the mechanism designed to protect the drug from gastric acids or prevent gastric mucosal irritation.

Crushing sublingual or buccal tabs can alter effectiveness.

Medications may be inappropriate to crush if they have enteric or slow-release coatings; are sublingual or buccal formulations; have the potential to irritate the skin or mouth when crushed; have antineoplastic, cytotoxic, or teratogenic properties; or have a potentially unacceptable taste.

Crushing enteric coated tablets may result in the drug being released too early, destroyed by stomach acid, or irritating the stomach lining.

In general, manipulation of enteric coated and extended-release formulations is not, therefore, recommended.

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