What is mitragynine toxicity?

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asked Apr 9, 2024 in Other- Health by FogHorn1989s (2,380 points)
What is mitragynine toxicity?

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answered Feb 9 by Nabilss (11,160 points)
Mitragynine toxicity is an overdose of mitragynine in the body which can cause respiratory depression, psychosis, seizure and even death.

Although there is not any consensus as to the lethal dose of mitragynine.

Mitragynine exerts it's effect on the central nervous system through modulation of mu-opioid receptors and monoamine receptors.

The mitragynine exhibitis effects like opium by interacting with the opioid receptors.

Mitragynine also interacts with serotonergic receptors and adrenergic receptors in your central nervous system.

Mitragynine also has anxiolytic, antidepressant, stimulant, sedative, anti inflammatory and antinociceptive affects.

Mitragynine is an opioid alkaloid that is found in the Kratom plant also known as the Mitragyna speciosa which produces pain relieving and euphoric effects

Mitragynine is an indole-based alkaloid.
And a psychoactive constituent of the kratom plant.
And is an opioid that is consumed for its pain-relieving and euphoric effects.
And is also a potential treatment for opioid withdrawal symptoms.

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