The time it takes for a twisted knee to heal is between 3 to 4 weeks but it depends on the severity of the Knee Sprain as well as the type of knee sprain.
But expect 3 to 4 weeks for the twisted knee to fully heal and for you to be back to normal.
More severe knee sprains can take as long as 4 to 12 months to fully heal back up to normal before you can get back to your normal activities.