How long has lybalvi been on the market?

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asked Feb 7 in Mental Health by nutswhencaght (1,560 points)
How long has lybalvi been on the market?

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answered Feb 7 by Gingerzebell (14,060 points)
Lybalvi has been on the market since October of 2021 and is available by prescription only and is FDA approved.

Lybalvi is not the same as olanzapine but Lybalvi also does contain olanzapine and samidorphan.

Lybalvi is better than olanzapine as it also contains samidorphan which is an opioid antagonist which decreases weight gain that olanzapine can cause.

People that take Lybalvi instead of olanzapine have less weight gain.

Samidorphan does help with weight loss as it's a mu-opioid receptor antagonist which has been found to reduce weight gain that is induced by olanzapine.

Samidorphan does cause weight gain although some people have experience some weight loss with Samidorphan so it can vary from person to person.

It is harder to lose weight on olanzapine as it can lead to an increase in weight gain and a better appetite.

Most people do gain weight with Lybalvi as well as olanzapine.

People who took Lybalvi experienced weight gain of 4.91% and those who took olanzapine experienced a weight gain of 6.77%.

Lybalvi is an atypical antipsychotic as it also contains olanzepaine and samidorphan which is an opioid antagonist.

Lybalvi causes weight gain because it can raise your blood sugar and cholesterol levels and increase your appetite which all can lead to weight gain when taking Lybalvi.

Lybalvi is not an opioid nor does it contain any opioid drugs.

Instead Lybalvi contains samidorphan which is an opioid antagonist that means that it blocks any opioids from working.

The bad side effects of Lybalvi are shaking, slow heartbeat, difficulty swallowing, fainting, mental and mood changes, confusion, restlessness, tingling and numbness of your legs and arms and yellowing of your skin and eyes and severe stomach and abdominal pain and trouble urinating.

If you experience any of the above serious side effects when taking Lybalvi you should tell your doctor right away.

Lybalvi is sedating and can make you sleepy or even dizzy and can cause a decrease in your blood pressure when changing position as well as slow your motor and thinking skills which can lead to falls.

The drug Lybalvi is used for treating mixed or manic episodes of bipolar 1 disorder, either alone for short term or for maintenance treatment or in a combination with valporate or lithium.

Lybalvi is a combination of two medications: olanzapine and samidorphan.

Olanzapine is a second-generation antipsychotic (also called an “atypical antipsychotic”) that has previously been sold by itself under the brand name Zyprexa.

Samidorphan is a new medication that hasn't been previously FDA-approved.

Lybalvi also contains the drug samidorphan, which is an opioid antagonist.

This drug was added to olanzapine to decrease the weight gain* that olanzapine may cause.

Although weight gain is still a possible side effect of Lybalvi, people who took Lybalvi reported less weight gain than those who took olanzapine alone.

LYBALVI may make you sleepy or dizzy, may cause a decrease in your blood pressure when changing position (orthostatic hypotension), and can slow your thinking and motor skills which may lead to falls that can cause fractures or other injuries or a low white blood cell count.

Lybalvi is not a controlled substance, which is a medication with a high risk of misuse.

With misuse, a person uses a drug in a way other than how a healthcare professional prescribes it.

Lybalvi is expensive and costs on average of $1,520.18 for 30 tablets of Lybalvi.

Side effects of Lybalvi include impaired body temperature regulation, heartburn, confusion, weakness, Tardive dyskinesia, Orthostatic hypotension, lung problems, Leukopenia, seizures, Dysphagia, Itchiness, headache, memory problems, weight gain, tingling or numbness, sleepiness, shaking, problems speaking, mouth watering, increased appetite, back pain, constipation, dry mouth and dizziness.

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