Demeclocycline is a diuretic as it causes water diuresis but it's not mainly a diuretic.
Demeclocycline is a tetracycline like antibiotic can also increase urine production and output so it can be seen as a diuretic.
Diuretics are medications that promotes diuresis which is the increase in urine production and excretion.
Demeclocycline is currently used in treating hyponatremia in people with SIADH, in which it can restore the plasma sodium concentrations to normal levels.
Demeclocycline is also used for therapy of mild to moderate infections as a result of susceptible organisms.
The side effects of demeclocycline on the kidneys include the inhibition of antidiuretic hormone ADH in your renal tubules.
The action produces nephrogenic diabetes insipidus, which results in polyuria and the inability to concentrate urine.
When taking demeclocycline it can make you sunburn more easily than normal.
So when taking demeclocycline you should avoid tanning beds and sunlight and wear protective clothing as well as use a sunscreen with an SPF of 30 or higher when you're outdoors.
And avoid taking any multivitamins, iron supplements, antacids, laxatives or calcium supplements too close to the time when taking demeclocycline.
The onset of action of demeclocycline is not predictable although it often occurs after 2 to 5 days but may take a bit longer.
The medications and supplements that interact with demeclocycline are laxatives containing magnesium, iron supplements, calcium supplements, calcium, aluminum and antacids containing magnesium.
Taking these supplements with demeclocycline makes the demeclocycline less effective.
You should also take the demeclocycline 2 hours before or 6 hours after taking antacids, laxatives containing magnesium and calcium supplements.