Where do sarcomas originate?

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asked Aug 23, 2023 in Diseases Conditions by GordonTom (3,220 points)
Where do sarcomas originate?

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answered Aug 29, 2023 by Gloverdragon (21,400 points)
Sarcomas originate in the connective tissue such as the muscle, bone and cartilage.

The sarcomas develop when the cells which make up these tissues called mesenchymal cells start to grow out of control.

And some types of sarcomas are found in children while others are more common in adults.

You should suspect sarcoma cancer if you notice large painless bumps that swell and become painful or if you notice bumps that suddenly appear and are soft but hard to move.

You can usually feel sarcoma cancer spread as they grow larger as when the sarcoma cancers grow larger they can cause pain and soreness by pressing on the nerves or muscles and eventually the sarcoma can spread to nearby organs as well.

Soft tissue sarcoma will usually feel like a soft and painless lump that cannot be moved easily.

You can sometimes feel a sarcoma lump although you may not feel the sarcoma lump until it has gotten bigger.

Most times you'll notice a soft and painless lump under the skin or deeper that cannot be moved easily and it will usually get bigger.

The beginning of sarcoma will look like swelling or a lump in the soft tissue of the body.

The sarcoma cancer can appear as a painless lump under your skin and it often appears on an arm or leg.

Sarcoma can also begin in the abdomen but may not cause signs or symptoms until they get very big.

Soft tissue sarcoma is not very common as soft tissue sarcoma only accounts for 1 percent of all cancers in adults.

The odds of getting sarcoma is 1 to 2 percent.

Sarcoma cancer accounts for 1 percent of adult cancers that are diagnosed in the United States and 15 to 20 percent for childhood sarcoma cancers.

Around 17,100 people in the United States are usually diagnosed with sarcoma cancer in the United States.

Sarcoma is a rare cancer that develops in the bones and soft tissues, including fat, muscles, blood vessels, nerves, deep skin tissues and fibrous tissues.

About 12,000 cases of soft tissue sarcomas and 3,000 cases of bone sarcomas are diagnosed in the U.S. each year.

Soft tissue sarcoma can be a serious medical issue.

Like many forms of cancer, doctors have more success treating soft tissue sarcomas if they diagnose the tumor before it spreads.

Without treatment, soft tissue sarcomas can spread (metastasize) and affect other areas of your body.

If the sarcoma cancer is found at an early enough stage and the sarcoma cancer has not spread from where it started, surgical treatment is often very effective and many people are cured.

However, if the sarcoma cancer has spread to other parts of the body, treatment can usually control the tumor but not cure it.

Some sarcoma cancers cannot be removed using surgery.

The 5-year survival rate for soft tissue sarcomas is about 65%.

The 5-year survival rate for cancer that has reached nearby organs or lymph nodes is about 50%.

Once soft tissue sarcoma has spread to other parts of the body, the 5-year survival rate is about 18%.

The warning signs of sarcoma cancer include.

A lump that can be felt through the skin that may or may not be painful.
Bone pain.
A broken bone that happens unexpectedly, such as with a minor injury or no injury at all.
Abdominal pain.
Weight loss.

Around 65 out of every 100 people (around 65%) with synovial sarcoma cancer in the limbs survive their cancer for 5 years or more after they are diagnosed.

Almost 40 out of every 100 people (almost 40%) with synovial sarcoma cancer in the trunk of the body survive their cancer for 5 years or more after they are diagnosed.

While sarcoma cancer may arise anywhere in the body, it most often originate in the arms, legs, chest, or abdomen.

Sarcomas are often not symptomatic until they are very large and may first be noticed as swelling or a painless lump.

Most stage II and III sarcomas are high-grade tumors.

They tend to grow and spread quickly.

Some stage III tumors have already spread to nearby lymph nodes.

Even when these sarcomas have not yet spread to lymph nodes, the risk of spread (to lymph nodes or other parts of the body) is very high.

The stages of soft tissue sarcomas range from stages I (1) through IV (4).

As a rule, the lower the number, the less the cancer has spread.

A higher number, such as stage IV, means cancer has spread more.

The vast majority of soft tissue sarcomas do not cause pain, which, unfortunately, leads people to mistakenly think they don't need an evaluation.

When a sarcoma is deep-seated, growing quickly, and located near sensitive areas like the sciatic nerve, it may be painful.

The most common sarcoma cancers are.

Gastrointestinal stromal tumor (GIST): GISTs begin in the gastrointestinal tract, usually in the stomach.
Liposarcoma: Tumors that begin in fatty tissue are known as liposarcoma.
Leiomyosarcoma: These tumors begin in the smooth muscle tissue that lines hollow organs.

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