The mortality rate for post splenectomy sepsis is 1.4%
The risk of infection and death among post splenectomy patients is 3.2% which a mortality rate of 1.4%
The most important risk post splenectomy is OPSI which is also called post splenectomy sepsis syndrome that is defined as generalized non specific flu like prodrome that is followed by rapid deterioration to full blown fulminant septic shock that can occur within 24 hours to 48 hours of the onset.
The most feared complication of splenectomy is an overwhelming post-splenectomy infection which is a rapidly progressive fulminant infection that is linked to spontaneous bacteremia and particularly involving S.
The vaccines you need if you don't have a spleen are.
Pneumococcal vaccine, PCV20 (Prevnar-20) – 0.5mL IM.
Haemophilus influenzae vaccine (HiB) – 0.5mL IM.
Meningococcal vaccine, MenACWY (Menquadfi/Menveo) – 0.5mL IM.
Serogroup B meningococcal, MenB-4C (Bexsero) – 0.5ml IM.
The infections that the spleen fights are germs in the blood and blood infections.
Your spleen controls the levels of white blood cells, red blood cells and the platelets that are the small cells that form blood clots.
The role of the spleen in autoimmune is to secrete factors that are required for the expansion and or activation of the SDMCs and establishing a niche for the cells.
The spleen filters the blood, removing and destroying bacteria and other infectious organisms in the bloodstream.
It also produces antibodies (immunoglobulins).
The 5 complications of splenectomy are bleeding, pulmonary embolism, pancreatitis/fistula, Atelectasis and pulmonary and abdominal sepsis.
You can donate blood if you don't have a spleen if the spleen was removed due to physical injury or trauma, although you must wait at least 6 months after you made a full recovery.
If your spleen was removed due to an illness such as lymphoma or thrombocytopaenic purpura then you cannot donate blood after the spleen was removed.
The 4 vaccines that are required after a splenectomy are.
Pneumococcal vaccine, PCV20 (Prevnar-20) – 0.5mL IM.
Haemophilus influenzae vaccine (HiB) – 0.5mL IM.
Meningococcal vaccine, MenACWY (Menquadfi/Menveo) – 0.5mL IM.
Serogroup B meningococcal, MenB-4C (Bexsero) – 0.5ml IM.
People without a functional spleen need to be vaccinated against pneumococcus, haemophilus influenzae type B, and meningococcus to reduce the risk of life-threatening infections.
When the spleen is removed the liver will then take over many of the functions of the spleen.
After the spleen is removed the liver will cope with most infections that the spleen used to deal with.
The cause of spleen death is transcapsular spleen rupture.
During a transcapsular spleen rupture the spleen capsule and parenchyma rupture simultaneously and then blood effuses into the peritoneal cavity and then leads to acute blood loss and immediate death.
You can live a normal life expectancy without a spleen although having no spleen puts you at greater risk of certain blood infections.
Your risk of blood infections without a spleen are highest in the first 2 years after the spleen was removed and stays the highest for the rest of your life.
You can live without a spleen, although without a spleen you can be at a greater risk for developing certain types of blood infections.
The degree of risk for blood infections without a spleen depends on your age and if you have other diseases.
However your risk of infection without a spleen is highest in the first two years after splenectomy, it stays high for the rest of your life.
Your spleen is a fist-sized organ found in the upper left side of your abdomen, next to your stomach and behind your left ribs.
The spleen is an important part of your immune system but you can survive without it because the liver can take over many of the spleen's functions.
The spleen and the gallbladder are peritoneal as the spleen and the gallbladder are contained in the peritoneal cavity.
The bladder is an retroperitoneal organ.
The urinary system including the urinary bladder and ureters are retroperitoneal organs which means they lie behind the peritoneum.
Intraperitoneal organs are the organs having a mesentery, such as the stomach, small intestine (jejunum and ileum), transverse colon, liver and gallbladder.
The difference between peritoneal and retroperitoneal is.
Intraperitoneal: peritonealized organs having a mesentery, such as the stomach, small intestine (jejunum and ileum), transverse colon, liver and gallbladder.
Retroperitoneal: organs without a mesentery and associated with posterior body wall, such as the aorta, inferior vena cava, kidneys and suprarenal glands.
The kidneys are called retroperitoneal because the kidneys sit behind a lining in your abdominal cavity, unlike all the other abdominal cavities.
The pancreas is called a retroperitoneal organ because it has no specific delineating anatomical structures and they have peritoneum on their anterior side only.
The human pancreas plays a big role in digestion and is located inside the abdomen, just behind the stomach.
Your pancreas is about the size of your hand.
During digestion, the pancreas makes pancreatic juices called enzymes.
These enzymes break down sugars, fats, and starches.
If you have a cancerous tumor on your pancreas you will usually live for around a year after diagnoses without treatment.
With treatment you may live for up to 5 years with the cancerous pancreas tumor.
Not all tumors on the pancreas are cancer so you may live a long life with the non cancerous tumor but the cancerous tumor can be and is deadly.
You can survive a pancreatic tumor if the tumor is caught soon enough and treated.
However without treatment you will die much sooner from the pancreatic tumor if it's cancerous and even with treatment you can still survive but not for too long.
You can remove a tumor from the pancreas through surgery and the whipple procedure.
Sometimes if a pancreatic NET is small, just the tumor itself is removed.
This is called enucleation. This operation may be done using a laparoscope, so that only a few small cuts on the belly are needed.
This operation may be all that is needed to treat an insulinoma.
A tumor on the pancreas can be either serious and cancerous or not serious and non cancerous.
Not all tumors on the pancreas turn out to be cancer and some tumors on the pancreas are harmless but even so you should get checked out.
If the tumor on your pancreas is cancerous then it's serious as it can be fatal if not removed or treated.
Chemo is worth it for pancreatic cancer if the pancreatic cancer has not progressed too far and you want to increase your life expectancy and live a bit longer.
Having chemo for pancreatic cancer can increase your lifespan so it can be worth it unless you're older and don't see it as worth it.