When did Oxervate come out?

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asked Aug 12, 2023 in Eye Health by jhgewy (2,500 points)
When did Oxervate come out?

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answered Aug 21, 2023 by Gingerzebell (18,940 points)
Oxervate first came out on August 22nd 2018.

Oxervate is the first application of a human nerve growth factor as a drug or treatment to be approved by the U.S. Food and Drug Administration (FDA).

Approved in August 2018, Oxervate is also the first topical biologic medication (i.e. a drug produced using a living system) approved in the field of ophthalmology.

OXERVATE is the only prescription eye drop that is FDA approved to treat neurotrophic keratitis.

Developed by Dompé, Oxervate was developed using the research findings of Rita Levi Montalcini, an Italian neurophysiologist that received a Nobel Prize in Medicine for the discovery of nerve growth factor.

Oxervate is a medicine used to treat neurotrophic keratitis, an eye condition in which damage to the trigeminal nerve supplying the surface of the eye causes loss of sensation and defects that do not heal naturally.

The medicine is only used in adults with moderate or severe disease.

OXERVATE is a lab developed form of nerve growth factor, which is thought to encourage faster corneal healing, help grow important cells in the cornea, and alleviate damage to the cornea caused by neurotrophic keratitis.

If you have dry eye symptoms or corneal damage, it might be time to try OXERVATE.

Eye discomfort, pain, redness, watery eyes, or temporary blurred vision may occur with the use of OXervate.

If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects.

Throw away the Oxervate vial no later than 12 hours from the time you connected the vial adapter to it even if there is eye solution still left in the vial.

Track each time you instill an eye drop of OXERVATE on the weekly Dose Recording Card provided with the delivery system.

Oxervate has been shown to increase by around 30-40% the number of people who achieve complete healing of the eye's surface when compared with eye drops containing no active substance.

Lenses may be reinserted 15 minutes after administration.

OXERVATE may cause mild to moderate eye discomfort such as eye pain during treatment.

“There are many safe and effective biologic treatments for NK including amniotic membrane, Oxervate (cenegermin 0.002%, Dompe), autologous serum eye drops (ASEDs) and platelet-rich plasma (PRP).

Oxervate is very expensive and costs as much as $48,498.00 per month.

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