Octinoxate is considered to be safe as oxtinoxate is approved for use in cosmetics worldwide; the maximum concentration in ready-for-use preparations varies according to local legislation.
And according to the U.S. FDA, the recommended use level for oxtinoxate is up to 7.5 percent.
Octyl methoxycinnamate or ethylhexyl methoxycinnamate or octinoxate, trade names Eusolex 2292 and Uvinul MC80, is an organic compound that is an ingredient in some sunscreens and lip balms.
It is an ester formed from methoxycinnamic acid and 2-ethylhexanol and is a liquid that is insoluble in water.
A limited amount of octinoxate in beauty and personal care products is the controversial norm in most of the world.
The FDA has determined that there's not yet enough evidence that it's harmful to humans to eliminate it from common use.
Although studies have shown it to cause harm to rats and the environment.
Octinoxate increases cell proliferation in cells that grow in response to estrogen exposure.
Lifetime estrogen exposure is an established risk factor in the development and progression of breast cancer.
Octinoxate affects other hormone systems as well.
There's no evidence that Octinoxate causes cancer (or hormonal disruption and any other health problems, for that matter).
Octinoxate may cause aging as it has been shown to generate free radicals in the skin when exposed to UV rays (10).
However, regular re-application of sunscreen may reduce the number of free radicals formed by chemical sunscreens.