Is tyrosine a stimulant?

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asked May 2, 2022 in Other- Health by JorelFlorke (8,300 points)
Is tyrosine a stimulant?

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answered May 2, 2022 by Dolcevita (8,460 points)
Tyrosine is not a stimulant itself but Tyrosine does work in conjunction with other stimulants such as methylphenidate (i.e. Ritalin).

Tyrosine can also help some people stay mentally sharp when you have lost sleep.

In one study, subjects were kept awake for over 24 hours.

Those who took tyrosine performed much better on two types of tasks than those who took a placebo.

The effect lasted around three hours.

Foods that are high in tyrosine include beef, pork, fish, chicken, tofu, milk, cheese, beans, seeds, nuts, and whole grains.

The reference dietary intake (RDI) of phenylalanine and tyrosine is 25mg per kilogram of body weight or 11mg per pound.

Tyrosine is found in soy products, chicken, turkey, fish, peanuts, almonds, avocados, bananas, milk, cheese, yogurt, cottage cheese, lima beans, pumpkin seeds, and sesame seeds.

Aromatic amino acids are actually relatively non polar.

Tyrosine's phenolic side chain has a hydroxyl substituent and tryptophan has a nitrogen atom in its indole ring sytem.

These residues are nearly always found to be largely buried in the hydrophobic interior of a proteins as they are prdeominantly non-polar in nature.

D phenylalanine is a type of amino acid.

The D-Phenylalanine is a synthetic dextro isomer of the phenylalanine which is an essential amino acid with anti-depressant and analgesic activities.

Also D-Phenylalanine is converted into tyrosine and tyrosine in turn is converted into L-dopa, norepinephrine, and epinephrine, three key neurotransmitters.

Phenylalanine is involved in the production of the neurotransmitters norepinephrine and dopamine, which are essential for the proper functioning of the brain and nervous system.

Phenylalanine also helps with the production of the pigment melanin, which gives color to the skin, hair, and eyes.

Phenylalanine is thought to mediate or exacerbate hepatic encephalopathy, and an impaired liver may not be able to cope with the ammoniagenic properties of the amino acid constituents, or adequately metabolize methanol.

Phenylalanine can cause intellectual disabilities, brain damage, seizures and other problems in people with PKU.

Phenylalanine occurs naturally in many protein-rich foods, such as milk, eggs and meat.

Phenylalanine is also sold as a dietary supplement.

A musty odor in the breath, skin or urine, caused by too much phenylalanine in the body.

Neurological problems that may include seizures.

Skin rashes (eczema) Fair skin and blue eyes, because phenylalanine can't transform into melanin — the pigment responsible for hair and skin tone.

The researchers found that the single-dose of phenylalanine reduced food intake, increased levels of GLP-1 and decreased levels of ghrelin.

Repeated administration also caused weight loss in the obese mice.

For best results, phenylalanine should be taken between meals, because the protein present in food can interfere with the uptake of phenylalanine into the brain, potentially reducing its effect.

D- and DL-phenylalanine are typically taken at a dose of 100 to 200 mg daily for the treatment of depression.

For the treatment of chronic pain, studies have used D-phenylalanine in doses as high as 2,500 mg daily.

High blood levels of phenylalanine can saturate the transport system across the blood-brain barrier and cause inhibition of the cerebral uptake of other large neutral amino acids such as branched-chain amino acids, tyrosine, and tryptophan, impairing brain protein synthesis.

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