How does vasopressin affect the kidneys?

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asked Apr 11, 2022 in Other- Health by R11988 (1,230 points)
How does vasopressin affect the kidneys?

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answered Apr 14, 2022 by Coffeemomma (16,800 points)
The way vasopressin affects the kidneys is by decreasing the water excretion by the kidneys by increasing water reabsorption in the collecting ducts.

It is concluded that physiological levels of vasopressin influence the distribution of renal blood flow by causing vasoconstriction in the outer region of the renal cortex.

Higher levels of the hormone increase vascular resistance throughout the cortex.

The effect of Vasopressin is it decreases the water excretion by the kidneys by increasing water reabsorption in the collecting ducts, hence its other name of antidiuretic hormone.

Vasopressin also has a potent constricting effect on arterioles throughout the body.

The main function of vasopressin is to maintain osmolality which is (the concentration of dissolved particles, such as salts and glucose, in the serum) and therefore in maintaining the volume of water in the extracellular fluid (the fluid space that surrounds cells).

Vasopression is used to treat low blood pressure and diabetes as well as treat frequent urination, increased thirst, and loss of water caused by diabetes insipidus.

Vasopressin works on the heart by increasing the maximum bradycardia that can be elicited through baroreceptor reflexes but does not alter the slope relating change in heart rate to change in blood pressure.

And vasopressin can cause coronary vasoconstriction or vasodilation and exert positive or negative inotropic effects.

In addition to its vascular effects on coronary blood flow, vasopressin also has mitogenic and metabolic effects on the heart.

Vasopressors work in the body to contract and tighten the blood vessels and raise blood pressure.

Vasopressors are a group of medicines that are used to treat severely low blood pressure, especially in people who are critically ill.

Very low blood pressure can lead to organ damage and even death.

An antihypotensive agent, also known as a vasopressor agent or simply vasopressor, or pressor, is any medication that tends to raise low blood pressure.

In theory, norepinephrine is the ideal vasopressor in the setting of warm shock, wherein peripheral vasodilation exists in association with normal or increased cardiac output.

Midodrine is a vasopressor and antihypotensive drug used to treat low blood pressure.

Midodrine is available under the following different brand names: ProAmatine, and Orvaten.

In the setting of IV administration, phenylephrine is a commonly used anesthetic vasopressor for patients with normal cardiac function and hypotension secondary to the vasodilatory effect of anesthetic medications or non-cardiac shock states.

The reason DDAVP is given to patients is to help stop bleeding in patients with von Willebrand's disease or mild hemophilia A.

When DDAVP is given it causes the release of von Willebrand's antigen from the platelets and the cells that line the blood vessels where it is stored.

Von Willebrand's antigen is the protein that carries factor VIII.

Desmopressin exerts its haemostatic effect by: Inducing synthesis of the von Willebrand factor (VWF) by endothelial cells.

Stimulating release of the VWF from its storage sites in endothelial cells.

Cleaving the large VWF multimers circulating in plasma into smaller multimers.

Desmopressin, sold under the trade name DDAVP among others, is a medication used to treat diabetes insipidus, bedwetting, hemophilia A, von Willebrand disease, and high blood urea levels.

Desmopressin is a man-made form of vasopressin and is used to replace a low level of vasopressin.

This medication helps to control increased thirst and too much urination due to these conditions, and helps prevent dehydration.

Desmopressin is also used to control nighttime bedwetting in children.

Desmopressin works by reducing the amount of urine produced in the body at night by the kidneys.

This means that the bladder then fills with less urine during the night.

Desmopressin is usually taken at bedtime.

Infrequently, desmopressin may affect your blood pressure.

It may cause an increase or decrease in your blood pressure.

A temporary drop in your blood pressure may result in dizziness and a fast heartbeat.

Ask your doctor for more details, especially if you have heart problems or high or low blood pressure.

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