High CRP can cause joint pain as it triggers inflammation which can lead to stiffness, swelling and pain of the joint.
People with joint pain and rheumatoid arthritis often have high or elevated levels of C-reactive protein or CRP and other proteins in their blood.
You should worry about CRP when the CRP levels are greater than 10 mg/dL which is considered a marked increase.
It's not clear if a minor rise of 0.3 to 1 mg/dL in CRP levels is a cause for concern although it could be.
The CRP level for active lupus is between 10 micrograms/ml and 50 micrograms/ml.
A normal CRP level for chronic inflammation is 0.3 to 1.0 mg/dL.
1.0 to 10.0 mg/dL is moderate elevation, more than 10.0 mg/dL is marked elevation and more than 50.0 mg/dL is severe elevation.
The cancers that have high C-reactive protein are pancreatic cancer, malignant lymphoma, non small cell lung cancer, colorectal cancer, renal cell carcinoma, breast cancer, prostate cancer and soft tissue sarcoma.
C-reactive protein is not a tumor marker although serum levels of C-reactive protein or CRP are often used as prognostic and risk markers in some cancers such as colorectal cancer, renal cell carcinoma, and lung cancer.
Serum CRP levels are also sometimes used as a prognostic marker in melanoma cancer.
C-reactive protein or CRP is an objective marker of inflammation and, in gastrointestinal diseases such as Crohn's disease and acute pancreatitis, it's levels correlate well with clinical disease activity.
The C-reactive protein is an annular pentameric protein that is found in blood plasma, whose circulating concentrations rise in response to inflammation.
C-reactive protein is an acute-phase protein of hepatic origin that increases following interleukin-6 secretion by macrophages and T cells.
Having high levels of CRP can mean you have a serious health condition that causes inflammation.
Inflammation is the body's way of protecting your tissues and helping them heal from an injury, infection, or other disease.
Inflammation in the body can be acute (sudden) and temporary.
More than 10.0 mg/dL: Marked elevation (Acute bacterial infections, viral infections, systemic vasculitis, major trauma).
More than 50.0 mg/dL: Severe elevation (Acute bacterial infections).
The best way to lower CRP is through exercise, weight loss, and dietary control and of course those are all proven already to lower vascular risk.
In a healthy adult, a CRP value less than 3 mg/L is considered normal.
The CRP values above 3 mg/L may indicate inflammation.
The degree of inflammation is often reflected in the magnitude of the CRP value, and higher levels may indicate more severe inflammation.