How aggressive is osteosarcoma?

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asked Jan 28 in Diseases Conditions by senztarrik (1,540 points)
How aggressive is osteosarcoma?

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answered Jan 29 by Amberwell (16,240 points)
Osteosarcoma is a very highly aggressive cancer and it spreads pretty fast.

The common age to be diagnosed with osteosarcoma is age 15 and boys and girls are just as likely to get osteosarcoma until their late teens.

Osteosarcoma is also common in people over the age of 60.

After surgery for osteosarcoma it can seem to take a long time before you can move around normally again and this may make you feel very low.

It can also take many months before you can weigh bear comfortably on your false limb.

And it may also take a while before your limb is completely comfortable.

Most people get there within a year of their surgery.

Osteosarcoma can be pretty painful although it most often causes a dull aching pain in the joint or bone around the tumor.

There is also often a firm swelling or lump in the area of the pain and the swelling is caused by the osteosarcoma tumor growing inside the bone.

The reason osteosarcoma is so painful is because osteosarcoma has both a nociceptive and neuropathic component and the nociceptive component is driven by the release of algogenic substances by tumor and their associated stromal cells, acidosis caused by bone-destroying osteoclasts, and mechanical destabilization and fracture of the bone.

The symptoms of osteosarcoma are bone pain, unexplained weight loss, fever, exhaustion, anemia and even redness and warmth at the site of the tumor and a bump depending on where the osteosarcoma tumor is located.

Osteosarcoma spreads very fast and by the time the osteosarcoma tumor has been found in the limb it is considered to have already spread and spreads to the lung in metastasis process which is a malignant process.

The causes of death in osteosarcoma patients is the progressive pulmonary metastasis with respiratory failure caused by widespread disease, superior vena cava obstruction, pneumothorax and pulmonary hemorrhage.

Osteosarcoma is fatal if not treated soon enough and even with treatment osteosarcoma can still be fatal although treatments can still help keep the osteosarcoma from spreading and improve your quality of life.

Osteosarcoma can be cured if caught early enough and if it has not spread to other parts of the body.

Around 3 out of 4 people with osteosarcoma are cured of it although many people that have osteosarcoma will also require physical therapy for several months after the surgery.

People who are most at risk for osteosarcoma are kids and teens between the ages of 10 to 19 and adults up to age 30 although adults can also get osteosarcoma at any age.

The age that osteosarcoma occurs is between the ages of 10 to 30 years of age.

Teens are the most commonly affected with osteosarcoma although it can occur at any age.

Around 1 in 10 cases of osteosarcomas occur in those older than 60 years of age.

The survival rate for osteosarcoma is 70 percent to 75 percent and if the osteosarcoma has spread to the lungs or other bones then the long term survival rate is around 30 percent.

The 2 types of osteosarcoma are.

Central tumor osteosarcoma which is also called a medullary tumor.
Surface tumor osteosarcoma which is also called a peripheral tumor.

Osteosarcoma is a form of bone cancer which usually develops in the osteoblast cells that form bones.

The bone cancer osteosarcoma occurs mostly in children, adolescents, and young adults.

Around 800 new cases of osteosarcoma are reported each year in the U.S. Of these cases, about 400 are in children and teens.

Osteosarcoma most often occurs in the long bones that make up the arms and legs, though it can occur in any bone.

It tends to occur in children and young adults.

Symptoms of osteosarcoma include localized bone pain and swelling.

Treatment for osteosarcoma typically involves surgery, chemotherapy, and radiation.

The good news is that 3 out of 4 people who have osteosarcoma can be cured if the osteosarcoma cancer hasn't spread to other parts of the body.

Almost everyone who is treated with limb-sparing surgery also ends up with that arm or leg working well.

Many people who have osteosarcoma will also need physical therapy for several months after surgery.

Osteosarcoma is the most common childhood cancer starting in bones, but is still fairly rare.

Each year, doctors diagnose just 1,000 cases in the U.S.

It's found most often in children and teens between the ages of 10 and 19. When it does occur in adults, people are usually in their 60s, 70s, or 80s.

Once tumor cells such as sarcoma, breast, prostate, thyroid, lung, and renal cancers begin to grow in the bone, a cycle of tumor growth, bone destruction, and formation of woven bone begins, which can result in considerable pain, skeletal fractures, and hypercalcemia.

Osteosarcoma is unfortunately a fast-spreading tumor.

By the time the tumor is found in the limb, it is considered to have already spread.

Osteosarcoma spreads to the lung in a malignant process called metastasis.

Osteosarcoma, the most common primary malignant bone tumor, is composed of spindle cells that produce osteoid.

It is a highly aggressive disease in which dramatic progress has been made in treatment and outcome over the past several decades.

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