How does Saxenda work for weight loss?

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asked May 31 in Weight Loss/Dieting by MoreMoats (1,020 points)
How does Saxenda work for weight loss?

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answered Jun 10 by Vivian232 (2,720 points)
Saxenda works for weight loss by slowing down your gastric motility and lower your Leptin Resistance.

First, and probably most important, is that GLP-1 agonists help lower leptin resistance.

You may not even realize it, but when it comes to weight loss leptin is probably the single most important hormone for determining if you will lose weight and how much weight you will lose.

Leptin is also responsible (at least in part) for the weight gain after rapid weight loss.

When taking Saxenda and injecting Saxenda everyday you can lose around 18.5 lbs per year.

That's not a lot of weight lost but using Saxenda does help get rid of some of your fat and weight although you lose more weight by exercising and burning off calories you intake along with taking Saxenda.

People who injected Saxenda (liraglutide) every day for a year lost an average of 18.5 pounds, compared with an average of 6 pounds for those taking a placebo, researchers found. Saxenda "can lower weight, improve cardiovascular risk factors and improve quality of life.

Saxenda is good for weight loss although you should still exercise and eat a healthy lower calorie diet when taking Saxenda to lose weight.

Saxenda can help you lose weight but you should also continue helping yourself lose weight naturally by doing the exercise, walking, jogging, running, bicycle riding, swimming and even change your diet to more healthy foods.

The side effects of taking Saxenda are.

Inflammation of the pancreas (pancreatitis). Stop using Saxenda® and call your healthcare provider right away if you have severe pain in your stomach area (abdomen) that will not go away, with or without vomiting.

You may feel the pain from your stomach area (abdomen) to your back.

Gallbladder problems. Saxenda® may cause gallbladder problems, including gallstones.

Some gallbladder problems need surgery. Call your health care provider if you have any of the following symptoms: pain in your upper stomach (abdomen), fever, yellowing of your skin or eyes (jaundice), or clay-colored stools.

Increased risk of low blood sugar (hypoglycemia) in adults with type 2 diabetes who also take medicines to treat type 2 diabetes such as sulfonylureas or insulin.

Risk of low blood sugar (hypoglycemia) in children who are 12 years of age and older without type 2 diabetes.

Signs and symptoms of low blood sugar may include: shakiness, sweating, headache, drowsiness, weakness, dizziness, confusion, irritability, hunger, fast heartbeat, and feeling jittery.

You should check your blood sugar before you start taking Saxenda® and while you take Saxenda®.

Increased heart rate. Saxenda® can increase your heart rate while you are at rest.

Your health care provider should check your heart rate while you take Saxenda®. Tell your health care professional if you feel your heart racing or pounding in your chest and it lasts for several minutes.

Kidney problems (kidney failure). Saxenda® may cause nausea, vomiting, or diarrhea leading to loss of fluids (dehydration).

Dehydration may cause kidney failure, which can lead to the need for dialysis.

This can happen in people who have never had kidney problems before.

Drinking plenty of fluids may reduce your chance of dehydration.

Call your health care provider right away if you have nausea, vomiting, or diarrhea that does not go away, or if you cannot drink liquids by mouth.

Serious allergic reactions.

Stop using Saxenda® and get medical help right away if you have any symptoms of a serious allergic reaction including swelling of your face, lips, tongue, or throat, fainting or feeling dizzy, very rapid heartbeat, problems breathing or swallowing, or severe rash or itching.

Depression or thoughts of suicide.

You should pay attention to any mental changes, especially sudden changes, in your mood, behaviors, thoughts, or feelings.

Call your health care provider right away if you have any mental changes that are new, worse, or worry you.

The most common side effects of Saxenda® in adults include nausea, diarrhea, constipation, vomiting, injection site reaction, low blood sugar (hypoglycemia), headache, tiredness (fatigue), dizziness, stomach pain, and change in enzyme (lipase) levels in your blood.

Additional common side effects in children are fever and gastroenteritis.

Saxenda® (liraglutide) injection 3 mg is an injectable prescription medicine used for adults with excess weight (BMI ≥27) who also have weight-related medical problems or obesity (BMI ≥30), and children aged 12-17 years with a body weight above 132 pounds (60 kg) and obesity to help them lose weight and keep the weight off.

Saxenda® should be used with a reduced calorie diet and increased physical activity.

Your body naturally produces an appetite hormone known as glucagon-like-peptide (GLP-1) that helps to regulate your hunger.

Saxenda® works like GLP-1 by regulating your appetite, which can lead to eating fewer calories and losing weight.

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